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Tisagenlecleucel Versus Standard of Care in Adult Patients With Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma: A Randomized, Open Label, Phase III Trial (BELINDA)

Trial Profile

Tisagenlecleucel Versus Standard of Care in Adult Patients With Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma: A Randomized, Open Label, Phase III Trial (BELINDA)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 15 Dec 2023

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At a glance

  • Drugs Tisagenlecleucel (Primary) ; Bendamustine; Carboplatin; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Etoposide; Fludarabine; Gemcitabine; Ibrutinib; Ifosfamide; Lenalidomide; Melphalan; Mesna; Oxaliplatin; Rituximab; Tocilizumab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms BELINDA
  • Sponsors Novartis; Novartis Pharma A.G.; Novartis Pharmaceuticals
  • Most Recent Events

    • 23 Jun 2023 This study has been completed in Belgium, according to European Clinical Trials Database.
    • 31 Oct 2022 Planned End Date changed from 16 Aug 2028 to 14 Feb 2026.
    • 31 Oct 2022 Planned primary completion date changed from 16 Aug 2028 to 13 Feb 2026.
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