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A Phase II Clinical Trial of Combination Nivolumab (Opdivo), Ipilimumab (Yervoy), and Paclitaxel in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (NSCLC) (The OPTIMAL Trial) [TOP 1705]

Trial Profile

A Phase II Clinical Trial of Combination Nivolumab (Opdivo), Ipilimumab (Yervoy), and Paclitaxel in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (NSCLC) (The OPTIMAL Trial) [TOP 1705]

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Jul 2023

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary) ; Paclitaxel (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use
  • Acronyms OPTIMAL; TOP 1705
  • Most Recent Events

    • 29 Jun 2023 Status changed from active, no longer recruiting to completed.
    • 22 Apr 2022 Time frame from primary endpoint changes from up to 5 years to up to 4 years
    • 22 Apr 2022 Planned End Date changed from 30 Jun 2023 to 12 Mar 2023.
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