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A Phase 2, Double-blind, Active-controlled, Dose-titrating Efficacy and Safety Study of Firibastat Compared to Ramipril Administered Orally, Twice Daily, Over 12 Weeks to Prevent Left Ventricular Dysfunction After Acute MI

Trial Profile

A Phase 2, Double-blind, Active-controlled, Dose-titrating Efficacy and Safety Study of Firibastat Compared to Ramipril Administered Orally, Twice Daily, Over 12 Weeks to Prevent Left Ventricular Dysfunction After Acute MI

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2023

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At a glance

  • Drugs Firibastat (Primary) ; Ramipril
  • Indications Heart failure; Left ventricular dysfunction; Myocardial infarction
  • Focus Therapeutic Use
  • Acronyms QUORUM
  • Sponsors Quantum Genomics
  • Most Recent Events

    • 14 Feb 2023 Status changed to completed, according to Results published in the American Journal of Cardiovascular Drugs
    • 09 Feb 2023 Primary endpoint has not been met (Left ventricular ejection fraction assessed by cardiac magnetic resonance imaging (CMRI)) , according to Results published in the American Journal of Cardiovascular Drugs
    • 09 Feb 2023 Results published in the American Journal of Cardiovascular Drugs

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