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A Global Randomized Multicenter Phase 3 Trial of JCAR017 Compared to Standard of Care in Adult Subjects With High-risk, Second-line, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)

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Trial Profile

A Global Randomized Multicenter Phase 3 Trial of JCAR017 Compared to Standard of Care in Adult Subjects With High-risk, Second-line, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Dec 2025

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At a glance

  • Drugs Lisocabtagene-maraleucel (Primary) ; Carboplatin; Carmustine; Cisplatin; Cyclophosphamide; Cytarabine; Dexamethasone; Etoposide; Fludarabine; Gemcitabine; Ifosfamide; Melphalan; Rituximab
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma; T-cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms TRANSFORM
  • Sponsors Celgene Corporation

Most Recent Events

  • 08 Dec 2025 According to Bristol-Myers Squibb media release, data from the trial were presented at the 67th American Society of Hematology (ASH) Annual Meeting.
  • 08 Dec 2025 Results presented in the Bristol-Myers Squibb Media Release
  • 01 Dec 2025 According to a Bristol Myers Squibb media release, data from the trial will be presented at the 67th American Society of Hematology (ASH) Annual Meeting

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