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A Global Randomized Multicenter Phase 3 Trial of JCAR017 Compared to Standard of Care in Adult Subjects With High-risk, Second-line, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)

Trial Profile

A Global Randomized Multicenter Phase 3 Trial of JCAR017 Compared to Standard of Care in Adult Subjects With High-risk, Second-line, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 08 Nov 2019

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At a glance

  • Drugs Lisocabtagene-maraleucel (Primary) ; Carmustine; Cyclophosphamide; Cytarabine; Etoposide; Fludarabine; Melphalan
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Follicular lymphoma; Non-Hodgkin's lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms TRANSFORM
  • Sponsors Celgene Corporation
  • Most Recent Events

    • 28 Feb 2019 Planned End Date changed from 15 Dec 2022 to 20 May 2023.
    • 28 Feb 2019 Planned primary completion date changed from 14 Oct 2022 to 20 May 2023.
    • 24 Jan 2019 Planned End Date changed from 13 Jan 2023 to 15 Dec 2022.
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