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A Randomized, Double-Blind, Vehicle-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenously Administered PRT064445 After Dosing to Steady State With One of Four Direct/Indirect fXa Inhibitors in Healthy Volunteers

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A Randomized, Double-Blind, Vehicle-Controlled Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenously Administered PRT064445 After Dosing to Steady State With One of Four Direct/Indirect fXa Inhibitors in Healthy Volunteers

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Andexanet alfa (Primary) ; Apixaban; Edoxaban; Enoxaparin sodium; Rivaroxaban
  • Indications Haemorrhage
  • Focus Therapeutic Use
  • Sponsors Portola Pharmaceuticals

    • Most Recent Events

    • 31 Aug 2018 The treatment arms and drug dosage has been amended.
    • 12 Jul 2018 New trial record

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