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A Phase 2 Study of Veliparib (ABT-888) and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients With Newly Diagnosed High-Grade Glioma (HGG) Without H3 K27M or BRAFV600 Mutations

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Trial Profile

A Phase 2 Study of Veliparib (ABT-888) and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients With Newly Diagnosed High-Grade Glioma (HGG) Without H3 K27M or BRAFV600 Mutations

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 May 2025

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At a glance

  • Drugs Temozolomide (Primary) ; Veliparib (Primary)
  • Indications Anaplastic astrocytoma; Glioblastoma; Glioma
  • Focus Therapeutic Use

Most Recent Events

  • 15 May 2025 Results published in the Neuro-Oncology
  • 13 Nov 2024 Planned End Date changed from 22 Sep 2024 to 16 Oct 2025.
  • 26 Sep 2023 Planned End Date changed from 17 May 2024 to 22 Sep 2024.

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