A Phase I, adaptive, open-label, single ascending dose to single-blind, placebo-controlled, multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of mRNA-0184 in participants with chronic heart failure
Latest Information Update: 20 Mar 2025
At a glance
- Drugs MRNA-0184 (Primary)
- Indications Chronic heart failure
- Focus Adverse reactions; First in man
- Sponsors AstraZeneca; Moderna Therapeutics
Most Recent Events
- 17 Mar 2025 Status changed from active, no longer recruiting to completed.
- 20 Nov 2023 Planned End Date changed from 7 May 2024 to 6 Mar 2025.
- 20 Nov 2023 Planned primary completion date changed from 7 May 2024 to 6 Mar 2025.