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A Phase 2 Open-Label Single-Arm Study to Evaluate the Efficacy and Safety of Loncastuximab Tesirine in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) (LOTIS-2)

Trial Profile

A Phase 2 Open-Label Single-Arm Study to Evaluate the Efficacy and Safety of Loncastuximab Tesirine in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (DLBCL) (LOTIS-2)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Jan 2024

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At a glance

  • Drugs Loncastuximab tesirine (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma
  • Focus Registrational; Therapeutic Use
  • Acronyms LOTIS 2
  • Sponsors ADC Therapeutics
  • Most Recent Events

    • 12 Dec 2023 Results presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 19 Oct 2023 Results assessing the prognosis of PET/CT-biomarkers in patients treated with loncastuximab tesirine published in the Clinical Cancer Research
    • 12 Sep 2023 Results presented at the 2023 American College of Clinical Pharmacology Annual Meeting

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