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An Open-Label, Investigator Study to Evaluate the Short-term (4 Weeks) Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR) With and Without CNS Manifestations

Trial Profile

An Open-Label, Investigator Study to Evaluate the Short-term (4 Weeks) Effects of TOLCAPONE on Transthyretin Stability in Subjects With Leptomeningeal TTR Amyloidosis (ATTR) With and Without CNS Manifestations

Status: Completed
Phase of Trial: Phase 0

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Tolcapone (Primary)
  • Indications Amyloidosis
  • Focus Pharmacodynamics; Proof of concept

Most Recent Events

  • 15 Sep 2020 According to a Corino Therapeutics media release, results from this study are presenting today at the XVII International Symposium on Amyloidosis.
  • 15 Sep 2020 Results presented at a Corino Therapeutics media release.
  • 12 Jun 2019 Status changed from active, no longer recruiting to completed.

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