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A Phase I Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 Following Single Ascending Dose Administration to Healthy Male Subjects With Elevated LDL-C Levels

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Trial Profile

A Phase I Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD8233 Following Single Ascending Dose Administration to Healthy Male Subjects With Elevated LDL-C Levels

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 09 Jun 2022

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At a glance

  • Drugs AZD-8233 (Primary)
  • Indications Cardiovascular disorders; Dyslipidaemias; Hypercholesterolaemia
  • Focus Adverse reactions; First in man
  • Sponsors AstraZeneca

    • Most Recent Events

    • 02 Jun 2022 Based on data from this study prespecified concentration-QT analysis was performed, published in the British Journal of Clinical Pharmacology.
    • 22 Jan 2021 Status changed from active, no longer recruiting to completed.
    • 17 Nov 2020 Results presented at the American Heart Association Scientific Sessions 2020

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