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Atezolizumab, Pertuzumab and Trastuzumab With Chemotherapy as Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer (APTneo)

Trial Profile

Atezolizumab, Pertuzumab and Trastuzumab With Chemotherapy as Neoadjuvant Treatment of HER2 Positive Early High-risk and Locally Advanced Breast Cancer (APTneo)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 29 Aug 2024

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At a glance

  • Drugs Atezolizumab (Primary) ; Pertuzumab (Primary) ; Pertuzumab (Primary) ; Trastuzumab (Primary) ; Trastuzumab emtansine (Primary) ; Anthracyclines; Carboplatin; Cyclophosphamide; Doxorubicin; Paclitaxel
  • Indications Advanced breast cancer; Early breast cancer; HER2 positive breast cancer; Inflammatory breast cancer
  • Focus Therapeutic Use
  • Acronyms APTneo; APTneo Michelangelo
  • Most Recent Events

    • 31 Jan 2024 Planned End Date changed from 15 Jun 2027 to 15 Mar 2027.
    • 31 May 2022 Status changed from recruiting to active, no longer recruiting.
    • 12 Feb 2019 Status changed from not yet recruiting to recruiting.

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