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A Phase 2, Multi-cohort, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With Clinical High-Risk Multiple Myeloma (KarMMa-2)

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Trial Profile

A Phase 2, Multi-cohort, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With Clinical High-Risk Multiple Myeloma (KarMMa-2)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Feb 2025

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At a glance

  • Drugs Idecabtagene vicleucel (Primary) ; Cyclophosphamide; Fludarabine; Lenalidomide
  • Indications Multiple myeloma
  • Focus Proof of concept; Therapeutic Use
  • Acronyms KarMMa-2
  • Sponsors Celgene Corporation

Most Recent Events

  • 14 Feb 2025 Status changed from recruiting to active, no longer recruiting.
  • 19 Nov 2024 According to a Bristol Myers Squibb media release, results from this trial will be presented at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition, to be held from December 7 to 10 in San Diego, California.
  • 23 May 2024 According to Bristol Myers Squibb media release, the company announced the presentation of data across its oncology and hematology portfolio at the upcoming 2024 American Society of Clinical Oncology (ASCO) Annual Meeting and the European Hematology Association (EHA) 2024 Hybrid Congress.

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