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A Multicenter Phase II Study Evaluating Denosumab (XGEVA®) in Combination with Nivolumab (OPDIVO®) As Second-line Therapy for Patients with Stage IV Non-small-cell Lung Cancer (squamous and Non-squamous) with Bone Metastases: DENIVOS STUDY

Trial Profile

A Multicenter Phase II Study Evaluating Denosumab (XGEVA®) in Combination with Nivolumab (OPDIVO®) As Second-line Therapy for Patients with Stage IV Non-small-cell Lung Cancer (squamous and Non-squamous) with Bone Metastases: DENIVOS STUDY

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Feb 2025

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At a glance

  • Drugs Denosumab (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Bone metastases; Non-small cell lung cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms DENIVOS

Most Recent Events

  • 13 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 25 Oct 2023 This trial has been completed in France(End Date: 19 Oct 2023), according to European Clinical Trials Database record.
  • 13 Sep 2022 Results presented at the 47th European Society for Medical Oncology Congress

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