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A Phase II Two Cohort Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

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Trial Profile

A Phase II Two Cohort Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 02 Dec 2019

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At a glance

  • Drugs Atezolizumab (Primary) ; Cobimetinib (Primary) ; Vemurafenib (Primary)
  • Indications Brain metastases; Malignant melanoma
  • Focus Therapeutic Use
  • Sponsors Roche

    • Most Recent Events

    • 03 Jul 2019 Planned End Date changed from 29 Mar 2023 to 28 Sep 2022.
    • 03 Jul 2019 Planned primary completion date changed from 29 Mar 2023 to 28 Sep 2022.
    • 04 Feb 2019 Status changed from not yet recruiting to recruiting.
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