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Randomized Phase 2 Clinical Trial of Nab-Paclitaxel + Durvalumab (MEDI4736) + Tremelimumab + Neoantigen Vaccine Vs. Nab-Paclitaxel + Durvalumab (MEDI4736) + Tremelimumab in Patients With Metastatic Triple Negative Breast Cancer

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Randomized Phase 2 Clinical Trial of Nab-Paclitaxel + Durvalumab (MEDI4736) + Tremelimumab + Neoantigen Vaccine Vs. Nab-Paclitaxel + Durvalumab (MEDI4736) + Tremelimumab in Patients With Metastatic Triple Negative Breast Cancer

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Mar 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Durvalumab (Primary) ; Gemcitabine (Primary) ; Paclitaxel (Primary) ; Peptide vaccines (Primary) ; Poly ICLC (Primary) ; Tremelimumab (Primary)
  • Indications Advanced breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 18 Dec 2024 Planned End Date changed from 31 Dec 2024 to 30 Nov 2025.
    • 18 Dec 2024 Planned primary completion date changed from 31 Dec 2024 to 30 Nov 2025.
    • 24 Dec 2022 Planned End Date changed from 31 Dec 2022 to 31 Dec 2024.

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