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A Randomized, Double-blind, Placebo-controlled, Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900, an Oral Plasma Kallikrein Inhibitor, in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II

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Trial Profile

A Randomized, Double-blind, Placebo-controlled, Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900, an Oral Plasma Kallikrein Inhibitor, in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Apr 2023

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At a glance

  • Drugs Sebetralstat (Primary)
  • Indications Hereditary angioedema
  • Focus Proof of concept; Registrational; Therapeutic Use
  • Sponsors KalVista Pharmaceuticals

    • Most Recent Events

    • 27 Feb 2023 Results assessing the effects of sebetralstat on cumulative HAE attack symptom severity, presented at the 2023 Annual Meeting of the American Academy of Allergy, Asthma and Immunology.
    • 27 Feb 2023 According to a KalVista Pharmaceuticals media release, data from this trial presented at the American Academy of Allergy, Asthma & Immunology (AAAAI) Annual Meeting in San Antonio, Texas.
    • 16 Feb 2023 According to a KalVista Pharmaceuticals media release, data from this study will be presented at the 2023 Annual Scientific Meeting for the American Academy of Allergy, Asthma & Immunology taking place in San Antonio, Texas from February 24-27. All results will be shared as a poster presentation and Q&A on Sunday, February 26 from 9:45-10:45 a.m. CST in the Convention Center, Lobby Level, Hall 2.

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