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Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Trial Profile

Treatment Free Remission After Combination Therapy With Ruxolitinib Plus Tyrosine Kinase Inhibitors in Chronic Phase Chronic Myeloid Leukemia (CP-CML) Patients Who Relapsed After a Prior Attempt at TKI Discontinuation

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Oct 2025

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At a glance

  • Drugs Bosutinib (Primary) ; Dasatinib (Primary) ; Imatinib (Primary) ; Nilotinib (Primary) ; Ruxolitinib (Primary)
  • Indications Chronic myeloid leukaemia
  • Focus Therapeutic Use

Most Recent Events

  • 19 Feb 2025 Planned End Date changed from 1 Dec 2026 to 1 Feb 2026.
  • 19 Feb 2025 Planned primary completion date changed from 1 Feb 2026 to 1 Feb 2025.
  • 19 Feb 2025 Status changed from recruiting to active, no longer recruiting.

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