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A phase II Study of Polatuzumab Vedotin (RO5541077) in Combination with Rituximab plus Bendamustine in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma

Trial Profile

A phase II Study of Polatuzumab Vedotin (RO5541077) in Combination with Rituximab plus Bendamustine in Patients with Relapsed or Refractory Diffuse Large B-cell Lymphoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Jun 2022

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At a glance

  • Drugs Bendamustine (Primary) ; Polatuzumab vedotin (Primary) ; Rituximab (Primary)
  • Indications Diffuse large B cell lymphoma
  • Focus Therapeutic Use
  • Acronyms P-DRIVE
  • Sponsors Chugai Pharmaceutical
  • Most Recent Events

    • 09 Jun 2022 Status changed from active, no longer recruiting to completed.
    • 01 Jul 2021 Results published in the Cancer Science
    • 23 Mar 2021 According to a Chugai Pharmaceutical media release, the Ministry of Health, Labour and Welfare (MHLW) approved Polivy (intravenous infusion 30mg and 140mg) in combination with bendamustine (freeze-dried formulation) and rituximab (BR therapy) for the treatment of relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL).
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