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An International, Double-blind, Randomised, Placebo-Controlled Phase III Study to Evaluate the Effect of Dapagliflozin on Reducing CV Death or Worsening Heart Failure in Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)

Trial Profile

An International, Double-blind, Randomised, Placebo-Controlled Phase III Study to Evaluate the Effect of Dapagliflozin on Reducing CV Death or Worsening Heart Failure in Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 05 Jan 2024

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms DELIVER
  • Sponsors AstraZeneca; AstraZeneca AB
  • Most Recent Events

    • 01 Dec 2023 Results of a patient level pooled analysis assessing efficacy of Dapagliflozin according to Heart Rate from two clinical trials: DAPA-HF and DELIVER trials published in the Circulation: Heart Failure
    • 13 Nov 2023 Results assessing whether higher BUN/Cr is associated with worse outcomes in patients with chronic HF by deriving data from PARADIGM-HF, ATMOSPHERE & DAPA-HF and PARAGON-HF & I-PRESERVE, published in the European Journal of Heart Failure
    • 13 Nov 2023 Results of patient-level pooled analysis of the DAPA-HF and DELIVER trials; comparing the baseline characteristics and outcomes by history of CABG and assessing efficacy and safety of dapagliflozin, presented at the American Heart Association Scientific Sessions 2023
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