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Phase 1, Open-label, Single Sequence, Two-Period Crossover Trial to Evaluate the Effect of Tepotinib on CYP3A by Investigating the PK of the CYP3A Substrate Midazolam in Healthy Subjects

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Trial Profile

Phase 1, Open-label, Single Sequence, Two-Period Crossover Trial to Evaluate the Effect of Tepotinib on CYP3A by Investigating the PK of the CYP3A Substrate Midazolam in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 Aug 2023

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At a glance

  • Drugs Tepotinib (Primary) ; Midazolam
  • Indications Liver cancer; Non-small cell lung cancer; Solid tumours
  • Focus Pharmacokinetics
  • Sponsors Merck KGaA

Most Recent Events

  • 27 Nov 2018 Status changed from not yet recruiting to completed.
  • 21 Aug 2018 New trial record

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