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A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Proof-of-Concept Study to Evaluate Guselkumab for the Treatment of Subjects With Moderate to Severe Hidradenitis Suppurativa

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A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Proof-of-Concept Study to Evaluate Guselkumab for the Treatment of Subjects With Moderate to Severe Hidradenitis Suppurativa

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 06 Feb 2025

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At a glance

  • Drugs Guselkumab (Primary) ; Guselkumab (Primary)
  • Indications Hidradenitis suppurativa
  • Focus Proof of concept; Therapeutic Use
  • Acronyms NOVA
  • Sponsors Janssen Research & Development; Janssen-Cilag

    • Most Recent Events

    • 01 Oct 2023 Primary endpoint of Percentage of Participants Achieving Hidradenitis Suppurativa Clinical Response (HiSCR) at Week 16, has not been met according to results presented in the Journal of the European Academy of Dermatology and Venereology.
    • 01 Oct 2023 Results evaluating effect of guselkumab presented in the Journal of the European Academy of Dermatology and Venereology.
    • 25 Jun 2020 Status changed from active, no longer recruiting to completed.

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