A Phase 2, Randomized, Dose-escalation, Ranibizumab-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of RGX-314 Gene Therapy Delivered Via One or Two Suprachoroidal Space (SCS) Injections in Participants With Neovascular Age-Related Macular Degeneration (nAMD) (AAVIATE)
Latest Information Update: 19 Nov 2024
At a glance
- Drugs Surabgene lomparvovec (Primary) ; Ranibizumab; Steroids
- Indications Wet age-related macular degeneration
- Focus Therapeutic Use
- Acronyms AAVIATE
- Sponsors AbbVie
Most Recent Events
- 12 Nov 2024 According to a Clearside Biomedical media release, this trial is enrolling a new cohort to evaluate dose levels for a planned pivotal program.
- 12 Aug 2024 According to a Clearside Biomedical media release, trial is initiating enrollment in a new cohort at dose level 4.
- 27 Jun 2024 Planned End Date changed from 1 Jan 2024 to 1 Aug 2026.