Trial Profile

Phase 1-2 Trial of Systemically Administered VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Selected Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 08 Oct 2025

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At a glance

Drugs Pembrolizumab (Primary) ; VSV-IFNbeta-NIS (Primary)
Indications Carcinoma; Neuroendocrine carcinoma; Non-small cell lung cancer; Renal cell carcinoma; Small cell lung cancer
Focus Adverse reactions; Therapeutic Use
Sponsors Vyriad

Most Recent Events

16 Sep 2025 Planned End Date changed from 31 Dec 2025 to 30 Sep 2025.
16 Sep 2025 Status changed from recruiting to active, no longer recruiting.
27 Dec 2024 Planned number of patients changed from 70 to 86.

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