Trial Profile

Basket of Baskets: A Modular, Open-label, Phase II, Multicentre Study To Evaluate Targeted Agents in Molecularly Selected Populations With Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 13 Jun 2025

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At a glance

Drugs Amivantamab (Primary) ; Atezolizumab (Primary) ; Futibatinib (Primary)
Indications Solid tumours
Focus Therapeutic Use
Acronyms BoB

30 Apr 2025 Results (n=84) assessing the exploratory endpoints evaluating a correlation of cfDNA and plasma proteomics dynamics with clinical benefit in arms 1A-1F of this study, presented at the 116th Annual Meeting of the American Association for Cancer Research.
09 Jun 2023 Number of treatment arms increased from 1 to 3 by the addition of Experimental: Module 2 - Futibatinib and Experimental: Module 3 - Amivantamab arms, thus adding 1 more study drugs. Janssen is added as a collaborator.
11 Oct 2022 Planned End Date changed from 1 Nov 2022 to 1 Nov 2026.

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