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A Multi-center, Randomized, Double Blind, Parallel-arm, Placebo Controlled Trial of Mepolizumab for Treatment of Adults and Adolescents With Active Eosinophilic Esophagitis and Dysphagia-predominant Symptoms

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Trial Profile

A Multi-center, Randomized, Double Blind, Parallel-arm, Placebo Controlled Trial of Mepolizumab for Treatment of Adults and Adolescents With Active Eosinophilic Esophagitis and Dysphagia-predominant Symptoms

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 28 Aug 2024

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At a glance

  • Drugs Mepolizumab (Primary)
  • Indications Deglutition disorders; Eosinophilic oesophagitis
  • Focus Therapeutic Use

    • Most Recent Events

    • 09 Jul 2023 Primary endpoint has not been met, (Mean Change in Dysphagia Score), as per Results published in the Gut
    • 09 Jul 2023 Results assessing whether mepolizumab more effective than placebo for improving dysphagia symptoms and decreasing oesophageal eosinophil counts in eosinophilic oesophagitis , published in the Gut
    • 20 Dec 2022 Status changed from active, no longer recruiting to completed.

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