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An Open Label Phase 1 Study of ADVM-022 (AAV.7m8-aflibercept) in Neovascular (Wet) Age-Related Macular Degeneration

Trial Profile

An Open Label Phase 1 Study of ADVM-022 (AAV.7m8-aflibercept) in Neovascular (Wet) Age-Related Macular Degeneration

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 25 Nov 2024

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At a glance

  • Drugs Ixoberogene soroparvovec (Primary)
  • Indications Wet age-related macular degeneration
  • Focus Adverse reactions; First in man
  • Acronyms OPTIC
  • Sponsors Adverum Biotechnologies

Most Recent Events

  • 18 Nov 2024 Results reporting new 4-year OPTIC long-term follow-up data presented in an Adverum Biotechnologies media release.
  • 04 Nov 2024 According to an Adverum Biotechnologies media release, 4-year OPTIC data anticipated in Q4 2024
  • 26 Sep 2023 According to an Adverum Biotechnologies media release, Presentation of OPTIC four-year Ixo-vec aflibercept protein expression data and three-year extension efficacy and safety data at the American Academy Ophthalmology (AAO) Meeting in November 2023.

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