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Effect of semaglutide once-weekly versus insulin aspart three times daily, both as add on to metformin and optimised insulin glargine (U100) in subjects with type 2 diabetes A 52-week, multi-centre, multinational, open-label, active-controlled, two armed, parallel-group, randomised trial in subjects with type 2 diabetes

Trial Profile

Effect of semaglutide once-weekly versus insulin aspart three times daily, both as add on to metformin and optimised insulin glargine (U100) in subjects with type 2 diabetes A 52-week, multi-centre, multinational, open-label, active-controlled, two armed, parallel-group, randomised trial in subjects with type 2 diabetes

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Jan 2023

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At a glance

  • Drugs Semaglutide (Primary) ; Insulin aspart; Insulin glargine; Metformin
  • Indications Type 2 diabetes mellitus
  • Focus Registrational; Therapeutic Use
  • Acronyms SUSTAIN 11
  • Sponsors Novo Nordisk
  • Most Recent Events

    • 16 Jan 2023 Results of cost-effectiveness analysis of Once-weekly semaglutide versus insulin aspart for the treatment of type 2 diabetes in the UK published in the Diabetes, Obesity and Metabolism
    • 02 Mar 2021 Status changed from active, no longer recruiting to completed.
    • 19 Nov 2020 Planned primary completion date changed from 29 Oct 2020 to 21 Jan 2021.

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