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An Open label, Multicentre, Phase I study of Ibrutinib and 3rd Party EBV specific T cells in Patients with immunosuppression related EBV-positive Brain and/or Systemic B cell lymphomas, that are relapsed/refractory or unsuitable for standard first-line treatments.

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Trial Profile

An Open label, Multicentre, Phase I study of Ibrutinib and 3rd Party EBV specific T cells in Patients with immunosuppression related EBV-positive Brain and/or Systemic B cell lymphomas, that are relapsed/refractory or unsuitable for standard first-line treatments.

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 18 Apr 2022

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At a glance

  • Drugs Epstein-Barr virus vaccine (Primary) ; Ibrutinib (Primary)
  • Indications B-cell lymphoma; Lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms TREBL-1

    • Most Recent Events

    • 27 Mar 2020 Planned End Date changed from 1 Dec 2024 to 20 Dec 2029.
    • 16 Jul 2019 Planned End Date changed from 1 Dec 2022 to 1 Dec 2024.
    • 16 Jul 2019 Status changed from not yet recruiting to recruiting.
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