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Phase1a, Randomized Placebo-controlled, Single and Multiple Dose, Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral NNI-362 in Healthy Aged Volunteers 50 to 72 Years of Age

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Trial Profile

Phase1a, Randomized Placebo-controlled, Single and Multiple Dose, Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Oral NNI-362 in Healthy Aged Volunteers 50 to 72 Years of Age

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 20 Feb 2023

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At a glance

  • Drugs NNI-362 (Primary)
  • Indications Alzheimer's disease
  • Focus Adverse reactions; First in man
  • Sponsors Neuronascent

    • Most Recent Events

    • 08 Nov 2022 According to Neuronascent media release, this study was fully supported by a grant from the National Institute on Aging (NIA, part of the National Institute of Health).
    • 08 Nov 2022 According to Neuronascent media release, the company announced its abstract entitled "Reduction of plasma p-Tau181 from a Phase 1a Randomized Trial of NNI-362 in a healthy aged population consistent with amelioration of tau hyperphosphorylation in human differentiated neuron cultures" has been accepted for a poster presentation at the 15th Clinical Trials on Alzheimer's Disease (CTAD 2022) to be held in San Francisco, California, USA from 29th November to 2nd December 2022.
    • 08 Nov 2022 Results published in the Neuronascent media release.
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