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A Phase Ib/II, Open-Label, Multicenter, Randomized, Controlled Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Patients With B-Cell Non-Hodgkin Lymphoma

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Trial Profile

A Phase Ib/II, Open-Label, Multicenter, Randomized, Controlled Study Investigating the Safety, Tolerability, Pharmacokinetics, and Efficacy of Mosunetuzumab (BTCT4465A) in Combination With CHOP or CHP-Polatuzumab Vedotin in Patients With B-Cell Non-Hodgkin Lymphoma

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Nov 2019

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Mosunetuzumab (Primary) ; Polatuzumab vedotin (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Tocilizumab (Primary) ; Vincristine (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Roche

    • Most Recent Events

    • 26 Feb 2019 Planned initiation date (estimated date of first participant enrollement) changed from 23 Feb 2019 to 15 Mar 2019.
    • 30 Jan 2019 Planned End Date changed from 2 Jul 2022 to 22 Jun 2022.
    • 30 Jan 2019 Planned primary completion date changed from 2 Jul 2022 to 22 Jun 2022.
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