Harnessing Olaparib, Palbociclib and Endocrine Therapy: a Phase I/II Trial of Olaparib, Palbociclib and Fulvestrant in Patients with BRCA Mutation-associated, Hormone Receptor-positive, Human Epidermal Growth Factor Receptor 2 (HER2)-negative Metastatic Breast Cancer (HOPE)
Latest Information Update: 06 Mar 2025
At a glance
- Drugs Fulvestrant (Primary) ; Olaparib (Primary) ; Palbociclib (Primary)
- Indications Advanced breast cancer; HER2 negative breast cancer
- Focus Therapeutic Use
- Acronyms HOPE
Most Recent Events
- 03 Mar 2025 Planned End Date changed from 1 Dec 2024 to 1 Aug 2025.
- 03 Mar 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Aug 2025.
- 29 Oct 2024 Planned End Date changed from 1 Apr 2024 to 1 Dec 2024.