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Effect of Evolocumab on Coronary Artery Plaque Volume and Composition by Coronary CTA (CCTA) and Microcalcification by F18-NaF PET: A Phase 3 Study

Trial Profile

Effect of Evolocumab on Coronary Artery Plaque Volume and Composition by Coronary CTA (CCTA) and Microcalcification by F18-NaF PET: A Phase 3 Study

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 23 Jul 2024

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At a glance

  • Drugs Evolocumab (Primary)
  • Indications Coronary artery disease; Hyperlipidaemia
  • Focus Therapeutic Use
  • Acronyms EVOLVE

Most Recent Events

  • 08 Apr 2024 Primary endpoint has been met. (Change in noncalcified coronary artery plaque volume (NCPV)), according to results presented at the 73rd Annual Scientific Session of the American College of Cardiology.
  • 08 Apr 2024 Results assessing effects of evolocumab on coronary atherosclerotic plaque composition and microcalcification activity presented at the 73rd Annual Scientific Session of the American College of Cardiology
  • 29 Aug 2023 Status changed from active, no longer recruiting to completed.

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