Trial Profile

Phase 2 Study of Ponatinib (Iclusig) for Prevention of Relapse After Allogeneic Stem Cell Transplantation (allo-SCT) in FLT3-ITD AML Patients: the PONALLO Trial

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 28 Mar 2025

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At a glance

15 Feb 2024 Planned End Date changed from 1 Jun 2024 to 31 Dec 2024.
12 Dec 2023 Status changed to discontinued, according to Results presented at the 65th American Society of Hematology Annual Meeting and Exposition
12 Dec 2023 Protocol has been amended after the 14th patient to start ponatinib between day 100 and day 120 post-allo, because of excesssive hematopoietic toxicity, according to Results presented at the 65th American Society of Hematology Annual Meeting and Exposition

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