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Additive diagnostic value of prostate specific membrane antigen (PSMA) positron emission tomography (PET) to multiparametric magnetic resonance imaging (mpMRI) in the diagnostic setting: Ability to reduce unnecessary prostate biopsies in men being investigated for prostate cancer.

Trial Profile

Additive diagnostic value of prostate specific membrane antigen (PSMA) positron emission tomography (PET) to multiparametric magnetic resonance imaging (mpMRI) in the diagnostic setting: Ability to reduce unnecessary prostate biopsies in men being investigated for prostate cancer.

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Nov 2022

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At a glance

  • Drugs 68-Ga-PSMA-617 (Primary)
  • Indications Prostate cancer
  • Focus Diagnostic use
  • Acronyms PRIMARY
  • Most Recent Events

    • 13 Nov 2022 Results of retrospective analysis (n=100) to identify synchronous reading of multiparametric MRI (mpMRI) and 68Ga-PSMA-11 PET/CT (PSMA-PET) images can improve diagnostic performance and certainty against mpMRI/PSMA-PET reported independently and synthesized, while also assessing concordance between imaging modalities and agreement with histopathology from the PRIMARY trial, published in the BJU International.
    • 18 Jul 2019 Planned initiation date changed from 29 Oct 2018 to 19 Jul 2019.
    • 18 Jul 2019 Planned End Date changed from 15 Apr 2019 to 30 Jun 2020.
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