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A Randomized, Multicenter, Double-Masked, Vehicle-Controlled Phase 2/3 Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With Persistent Corneal Epithelial Defects (NEXPEDE-1)

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Trial Profile

A Randomized, Multicenter, Double-Masked, Vehicle-Controlled Phase 2/3 Study to Evaluate the Safety and Efficacy of NEXAGON® (Lufepirsen Ophthalmic Gel) in Subjects With Persistent Corneal Epithelial Defects (NEXPEDE-1)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Aug 2024

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At a glance

  • Drugs Lufepirsen (Primary)
  • Indications Corneal injuries
  • Focus Therapeutic Use
  • Acronyms NEXPEDE-1
  • Sponsors Amber Ophthalmics

Most Recent Events

  • 01 Aug 2024 Planned number of patients changed from 120 to 84.
  • 01 Aug 2024 Planned End Date changed from 1 Oct 2024 to 1 Dec 2025.
  • 01 Aug 2024 Planned primary completion date changed from 1 Oct 2024 to 1 Dec 2025.

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