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An Open-label, Phase I Study to Assess the Safety of Multiple Doses of CYAD-101, Administered After Standard FOLFOX or FOLFIRI Chemotherapy in Patients With Unresectable Metastatic Colorectal Cancer

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An Open-label, Phase I Study to Assess the Safety of Multiple Doses of CYAD-101, Administered After Standard FOLFOX or FOLFIRI Chemotherapy in Patients With Unresectable Metastatic Colorectal Cancer

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 20 Oct 2022

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At a glance

  • Drugs CYAD 101 (Primary) ; Fluorouracil; Folinic acid; Irinotecan; Oxaliplatin
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions; First in man
  • Acronyms alloSHRINK
  • Sponsors Celyad Oncology

    • Most Recent Events

    • 12 Oct 2022 According to a Celyad Oncology media release, the company has decided to discontinue the development of CYAD-101, based on a strategic, financial and medical review, taking into account the costs associated with the pursuit of the program and the delays to reach key medical milestones following the resolution of the previous Clinical Hold. There were no new safety concerns leading to this decision. All patients in trials will continue to receive their protocol-defined follow-up.
    • 12 Oct 2022 Status changed from recruiting to discontinued, according to a Celyad Oncology media release.
    • 06 May 2021 According to a Celyad Oncology media release, the Company expects to announce preliminary data from the expansion cohort of the trial in mid-2021.

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