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A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In)

Trial Profile

A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In)

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 12 Mar 2024

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At a glance

  • Drugs Brazikumab (Primary) ; Brazikumab (Primary) ; Adalimumab
  • Indications Crohn's disease
  • Focus Biomarker; Therapeutic Use
  • Acronyms INTREPID
  • Sponsors AbbVie; Allergan; AstraZeneca; AstraZeneca AB

Most Recent Events

  • 23 Nov 2023 This trial has been completed in Germany (global end date: 2023-10-18), according to European Clinical Trials Database.
  • 20 Nov 2023 Status changed from active, no longer recruiting to discontinued.
  • 06 Sep 2023 This trial has been discontinued in Spain (Date of the global end of the trial: 01-Jun-2023), according to the European Clinical Trials Database record.

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