A Phase 1/2a Study in 3 Parts to Evaluate Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of MIV-818 in Patients With Liver Cancer Manifestations
Latest Information Update: 24 Feb 2025
At a glance
- Drugs Fostroxacitabine bralpamide (Primary) ; Lenvatinib (Primary) ; Pembrolizumab (Primary)
- Indications Cholangiocarcinoma; Liver cancer; Liver metastases
- Focus Adverse reactions; First in man; Therapeutic Use
- Sponsors Medivir AB
Most Recent Events
- 20 Feb 2025 According to a Medivir AB media release, The positive, final data from this study in advanced liver cancer (hepatocellular carcinoma/HCC) at the EASL (European Association for the Study of the Liver) Liver Cancer Summit in Paris, France.
- 20 Feb 2025 Results presented in the Medivir AB media release.
- 19 Dec 2024 According to a Medivir AB media release, this phase 1b/2a combination study in HCC was completed in Nov 2024, The three patients still remaining on treatment after more than 15 months have been transitioned to compassionate use, allowing them continued benefit from the study drug. End of treatment safety and efficacy data will be presented at the conference in Paris.