Trial Profile
Open-Label Phase 1b/2a Clinical Trial to Assess the Safety, Tolerability and Antitumor Activity of Genetically Engineered NY-ESO-1 Specific (c259) T Cells (GSK3377794) in Combination With Anti-Cancer Agents Including Pembrolizumab in HLA-A2+ Participants With NY-ESO-1 and/or LAGE-1a Positive Relapsed and Refractory Synovial Sarcoma
Status:
Withdrawn prior to enrolment
Phase of Trial:
Phase II
Latest Information Update: 16 May 2022
Price :
$35
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At a glance
- Drugs Cyclophosphamide (Primary) ; Fludarabine (Primary) ; Letetresgene autoleucel (Primary) ; Pembrolizumab (Primary)
- Indications Synovial sarcoma
- Focus Adverse reactions
- Sponsors GlaxoSmithKline; GSK
- 07 Mar 2019 Planned End Date changed from 17 Jul 2022 to 18 Jul 2022.
- 07 Mar 2019 Planned primary completion date changed from 17 Jul 2022 to 18 Jul 2022.
- 07 Mar 2019 Status changed from not yet recruiting to withdrawn prior to enrolment.