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Phase 1b/2 Study of BXCL701, a Small Molecule Inhibitor of Dipeptidyl Peptidases, Administered in Combination With the Anti-Programmed Cell Death 1 Monoclonal Antibody Pembrolizumab in Patients With Small Cell Neuroendocrine Prostate Cancer
Phase 1b/2 Study of BXCL701, a Small Molecule Inhibitor of Dipeptidyl Peptidases, Administered in Combination With the Anti-Programmed Cell Death 1 Monoclonal Antibody Pembrolizumab in Patients With Small Cell Neuroendocrine Prostate Cancer
Status:Recruiting
Phase of Trial:
Phase I/II
Latest Information Update:31 May 2020
Price :
$35
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Indications
Adenocarcinoma; Neuroendocrine carcinoma; Prostate cancer
Focus
First in man; Therapeutic Use
Sponsors
BioXcel Therapeutics
Most Recent Events
31 May 2020
Results presented at the 56th Annual Meeting of the American Society of Clinical Oncology
28 Apr 2020
According to a BioXcel Therapeutics media release, in the phase II efficacy portion of the trial, approximately 30 patients will receive 0.3 mg of BXCL701 twice daily (BID) on days 1 through 14 of a 21-day cycle plus 200 mg of pembrolizumab administered intravenously on day 1 and every subsequent 21 days.
28 Apr 2020
Results from the Phase 1b safety assessment, presented in a BioXcel Therapeutics media release.
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