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A Phase IIa trial of Ampligen (rintatolimod) in combination with checkpoint inhibitors for the treatment of advanced urothelial cancer, renal cell carcinoma and Melanoma (Second line therapy or greater, combination therapy)

Trial Profile

A Phase IIa trial of Ampligen (rintatolimod) in combination with checkpoint inhibitors for the treatment of advanced urothelial cancer, renal cell carcinoma and Melanoma (Second line therapy or greater, combination therapy)

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 16 Jan 2020

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At a glance

  • Drugs Rintatolimod (Primary) ; Immunotherapies
  • Indications Malignant melanoma; Renal cell carcinoma; Urogenital cancer
  • Focus Therapeutic Use
  • Most Recent Events

    • 08 Aug 2019 According to a Hemispherx Biopharma media release, Dr. David Strayer is the Principal Investigator
    • 17 Oct 2018 New trial record
    • 10 Oct 2018 According to Hemispherx Biopharma media release, this trial will be led by Pawel Kalinski, MD, PhD, Vice Chair for Translational Research and Professor of Oncology in the Department of Medicine and Co-Leader of the Tumor Immunology and Immunotherapy Program at Roswell Park, in collaboration with Mateusz Opyrchal, MD, PhD, of the Roswell Park Department of Medicine.
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