Phase Ib Trial With Dose Expansion of the Bruton"s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)
Latest Information Update: 02 Feb 2026
At a glance
- Drugs Ibrutinib (Primary) ; Lenalidomide; Rituximab
- Indications Diffuse large B cell lymphoma; Nervous system neoplasms
- Focus Adverse reactions
Most Recent Events
- 29 Jan 2026 Status changed from active, no longer recruiting to completed.
- 02 Dec 2025 Planned End Date changed from 1 Nov 2025 to 1 Nov 2026.
- 02 Dec 2025 Planned primary completion date changed from 1 Nov 2025 to 1 Nov 2026.