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Phase Ib Trial With Dose Expansion of the Bruton"s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

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Trial Profile

Phase Ib Trial With Dose Expansion of the Bruton"s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Dec 2023

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At a glance

  • Drugs Ibrutinib (Primary) ; Lenalidomide; Rituximab
  • Indications Diffuse large B cell lymphoma; Nervous system neoplasms
  • Focus Adverse reactions

    • Most Recent Events

    • 18 Dec 2023 Planned End Date changed from 1 Nov 2023 to 1 Nov 2024.
    • 18 Dec 2023 Planned primary completion date changed from 1 Nov 2023 to 1 Nov 2024.
    • 11 Aug 2022 Status changed from recruiting to active, no longer recruiting.
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