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Phase Ib Trial With Dose Expansion of the Bruton‟s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Trial Profile

Phase Ib Trial With Dose Expansion of the Bruton‟s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Apr 2019

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At a glance

  • Drugs Ibrutinib (Primary) ; Lenalidomide; Rituximab
  • Indications Diffuse large B cell lymphoma; Nervous system neoplasms
  • Focus Adverse reactions
  • Most Recent Events

    • 22 Jan 2019 Status changed from not yet recruiting to recruiting.
    • 15 Jan 2019 Planned initiation date changed from 1 Dec 2018 to 1 Jan 2019.
    • 04 Dec 2018 Planned initiation date changed from 1 Nov 2018 to 1 Dec 2018.
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