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Phase Ib Trial With Dose Expansion of the Bruton"s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Trial Profile

Phase Ib Trial With Dose Expansion of the Bruton"s Tyrosine Kinase (BTK) Inhibitor, Ibrutinib, in Combination With Rituximab and Lenalidomide in Patients With Refractory/Recurrent Primary Central Nervous System Lymphoma (PCNSL) and Refractory/Recurrent Secondary Central Nervous System Lymphoma (SCNSL)

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 12 Dec 2024

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At a glance

  • Drugs Ibrutinib (Primary) ; Lenalidomide; Rituximab
  • Indications Diffuse large B cell lymphoma; Nervous system neoplasms
  • Focus Adverse reactions

Most Recent Events

  • 10 Dec 2024 Planned End Date changed from 1 Nov 2024 to 1 Nov 2025.
  • 10 Dec 2024 Planned primary completion date changed from 1 Nov 2024 to 1 Nov 2025.
  • 18 Dec 2023 Planned End Date changed from 1 Nov 2023 to 1 Nov 2024.

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