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Phase I/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With R-CHOP in a Cohort of Patients With DLBCL/tFL/ High Grade B-NHL

Trial Profile

Phase I/II Study to Evaluate the Safety and Efficacy of Nivolumab in Combination With R-CHOP in a Cohort of Patients With DLBCL/tFL/ High Grade B-NHL

Status: Suspended
Phase of Trial: Phase I/II

Latest Information Update: 30 Jan 2024

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At a glance

  • Drugs Cyclophosphamide (Primary) ; Doxorubicin (Primary) ; Nivolumab (Primary) ; Prednisone (Primary) ; Rituximab (Primary) ; Vincristine (Primary)
  • Indications B-cell lymphoma; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 12 Dec 2023 Results evaluating safety and preliminary efficacy nivolumab in combination with R-CHOP in pts with DLBCL, presented at the 65th American Society of Hematology Annual Meeting and Exposition
  • 11 Aug 2022 Planned End Date changed from 11 Jun 2023 to 11 Jun 2025.
  • 11 Aug 2022 Planned primary completion date changed from 11 May 2022 to 11 Dec 2024.

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