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A Clinical Trial to Evaluate the Impact of Broadly Neutralizing Antibodies VRC01LS and 10-1074 on Maintenance of HIV Suppression in a Cohort of Early-Treated Children in Botswana (Dual bNAb Treatment in Children)

Trial Profile

A Clinical Trial to Evaluate the Impact of Broadly Neutralizing Antibodies VRC01LS and 10-1074 on Maintenance of HIV Suppression in a Cohort of Early-Treated Children in Botswana (Dual bNAb Treatment in Children)

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 23 Apr 2024

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At a glance

  • Drugs VRC 01LS (Primary) ; Zinlirvimab (Primary) ; Antiretrovirals
  • Indications HIV infections
  • Focus Adverse reactions; Proof of concept; Therapeutic Use

Most Recent Events

  • 06 Mar 2024 Results assessing findings for additional biomarker combinations, at entry to and during the bNAb-only step of the study, presented at the 31st Conference on Retroviruses and Opportunistic Infections 2024.
  • 22 Feb 2023 Results presented at the 30th Conference on Retroviruses and Opportunistic Infections 2023
  • 15 Sep 2022 Results evaluating the safety and pharmacokinetics of dual intravenous VRC01LS and 10-1074 in very early-treated children with HIV-1, published in the JAIDS

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