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A Phase 2a Clinical Trial of of VAR 200 (2-hydroxypropyl-ß-cyclodextrin, or HPßCD) in Adult Patients with Focal Segmental Glomerulosclerosis (FSGS)

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Trial Profile

A Phase 2a Clinical Trial of of VAR 200 (2-hydroxypropyl-ß-cyclodextrin, or HPßCD) in Adult Patients with Focal Segmental Glomerulosclerosis (FSGS)

Status: Planning
Phase of Trial: Phase II

Latest Information Update: 14 Apr 2026

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At a glance

  • Drugs Hydroxypropyl betadex (Primary)
  • Indications Focal segmental glomerulosclerosis
  • Focus Proof of concept; Therapeutic Use

Most Recent Events

  • 01 Apr 2026 According to a ZyVersa Therapeutics media release, company expect to initiate the trial in Q2-2026; Interim Phase 2a read-out expected in Q4-2026.
  • 14 Dec 2023 According to a ZyVersa Therapeutics media release, company announced selection of contract research organization George Clinical to manage this trial.
  • 21 Aug 2023 According to a ZyVersa Therapeutics media release, initial patient enrollment is expected by the first quarter of 2024.

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