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A Phase II Study to Evaluate the Safety and the Efficacy of a Blinatumomab Based Consolidation and Maintenance in Patients With High-risk B-cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL). GRAALL-QUEST

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Trial Profile

A Phase II Study to Evaluate the Safety and the Efficacy of a Blinatumomab Based Consolidation and Maintenance in Patients With High-risk B-cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL). GRAALL-QUEST

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 16 Jan 2024

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At a glance

  • Drugs Blinatumomab (Primary)
  • Indications Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use
  • Acronyms Graall-2014-QUEST; GRAALL-QUEST

    • Most Recent Events

    • 12 Dec 2023 Results identifying patient- and disease-related factors associated with response to BLIN, and to understand how BLIN influences the outcome after allo-HSCT, presented at the 65th American Society of Hematology Annual Meeting and Exposition
    • 13 Dec 2022 Primary endpoint (Disease Free Survival Y3) has been met, as per results presented at the 64th American Society of Hematology Annual Meeting and Exposition.
    • 13 Dec 2022 Results (n=489; Between December 2015 and December 2020) comparing (QUEST cohort (n=93) was compared to the control cohort (n=104)) their outcome to that of similar patients treated in the same GRAALL-2014/B trial but without frontline blinatumomab, presented at the 64th American Society of Hematology Annual Meeting and Exposition.

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