Trial Profile
A Phase 1/2 Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
Status:
Active, no longer recruiting
Phase of Trial:
Phase I/II
Latest Information Update: 20 Nov 2023
Price :
$35
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At a glance
- Drugs Binimetinib (Primary) ; Crizotinib (Primary) ; Darovasertib (Primary)
- Indications Colorectal cancer; Malignant melanoma; Skin cancer; Solid tumours; Uveal melanoma
- Focus Adverse reactions; Pharmacokinetics; Proof of concept; Registrational; Therapeutic Use
- Sponsors IDEAYA Biosciences
- 24 Oct 2023 Results (At data cut-off : 08 Mar2023; n=68) assessing ctDNA reduction and clinical efficacy of the darovasertib plus crizotinib combination in metastatic uveal melanoma, presented at the 48th European Society for Medical Oncology Congress.
- 17 Oct 2023 Results presented in the IDEAYA Biosciences Media Release.
- 10 Aug 2023 According to an IDEAYA Biosciences media release, data from this trial will be presented as oral presentation at ESMO 2023 scheduled for Monday, October 23, 2023.